Cholesterol
Colorimetric
| REF | Volume |
|---|---|
| N/A | N/A |
Product description:
Cholesterol is the precursor of all steroid hormones, cholesterol esters, and bile acids, and is
a component of the plasma membrane of cells. Total cholesterol consists of free cholesterol and
cholesterol esters. Serum cholesterol is derived from the diet and is synthesized in the liver.
Low-density lipoproteins (LDLs) consist mostly of protein, are rich in cholesterol, and are
derived from the breakdown of very low-density lipoproteins (VLDLs). High-density lipoproteins
(HDLs), the smallest particles, consist mostly of cholesterol, protein, and phospholipids, with
only a small quantity of triglycerides. LDLs are a source of cholesterol for peripheral cells,
such as the adrenal gland; HDLs transport cholesterol from peripheral cells back to the liver.
LDLs and HDLs do no contribute to visible lipaemia. Excess cholesterol is excreted via the bile,
where it is esterified. Cholesterol measurements can provide supportive evidence in some
diseases.
Blood cholesterol level is affected by a number of factors, including genetics, diet, and
tobacco usage, level of physical activity, age, and menopause. Quantification of total
cholesterol allows the detection of hypercholesterolemia, isolated or associated with
hypertriglyceridemia. High cholesterol concentrations are associated with a high risk for
vascular accident and apparition of atherosclerosis. The LDL/HDL ratio should be taken in
consideration for evaluating the risk of developing cardiovascular diseases.
